The NIH Blueprint Non-Human Primate (NHP) Atlas consists of a suite of gene expression data,
neuroanatomical data and informatics tools for exploring the cellular and
molecular architecture of the developing rhesus macaque brain.
Funding Support
The NIH Blueprint Non-Human Primate (NHP) Atlas, http://www.blueprintnhpatlas.org,
is funded from Federal funds from the National Institutes of Mental Health, Department of Health and
Human Services,
under Contract HHSN-271-2008-0047-C to the Allen Institute for Brain Science (Seattle, WA).
The content is solely the responsibility of the authors and does not necessarily
represent the official views of the National Institutes of Health.
CONTRIBUTORS
IN ASSOCIATION WITH
Data Overview
The NIH Blueprint Non-Human Primate (NHP) Atlas includes the following
Microarray
Microdissection:
Fine structure transcriptional profiling across prenatal and postnatal development for fine nuclear
subdivisions of the prefrontal cortex, primary visual cortex, hippocampus, amygdala and ventral
striatum
Macrodissection:
Gross structure transcriptional profiling across postnatal development for the same structures
Cellular resolution in situ hybridization image data of five major brain regions during
postnatal developmental periods for genes clinically important for a variety of human
neurodevelopmental disorders
Serial analysis of selected genes across the entire adult brain, focusing on cellular marker genes,
genes with cortical area specificity and gene families important to neural function.
Whole brain serial analysis of genes ENC1 and GAP43 to aid neuroanatomical delineations for prenatal microdissection microarray.
Detailed gene expression search on the ISH data based on expert annotation.
Developmental stage-specific reference series, consisting of magnetic resonance imaging (MRI) and
Nissl histology to provide a neuroanatomical context for the gene expression data.
A set of supporting data containing histological stains to assist in neuroanatomical delineations for prenatal microdissection microarray.
